Download this PDF book: Synthetic Organic Chemistry and the Nobel Prize Volume 1 By John G. D'Angelo
The Nobel Prize—a prize recognized at least in name—as one of the, if not THE, premier rewards for genius is arguably the most famous award in the world.
It is unlikely that someone past a High School education has never heard of the Nobel Prize. Awarded (mostly) annually since 1901 in the subjects of Chemistry, Physics, Physiology or Medicine, Peace, and Literature and joined in 1968 by the Sveriges Riksbank Prize in Economic Sciences in memory of Alfred Nobel (Figure 0.1), these prizes carry a medal, diploma, and cash prize for those chosen for this high honor in addition to the accompanying recognition.
It is important to note that the Economic Sciences prize is, formally speaking, not a Nobel Prize, though they’re awarded at the same time and this prize is treated very much like a Nobel. The prize was created by Alfred Nobel in 1895 in his last will and testament, with the largest share of his considerable fortune allocated to the series of prizes. The “rules” set out in Nobel’s will about the award are still at least mostly adhered to today, over a century later.
The chief difference is that although Nobel stipulated that the award should be made for a scientific matter from the preceding year, it appears (to me anyway) that it has more recently become more of a lifetime achievement award of sorts, at least in the life and physical sciences awards (Chemistry, Physiology or Medicine, and Physics).
Exactly when this started is difficult to pin down, but it is very clearly the current modus operandi. The primary source of Nobel’s wealth was as the inventor of dynamite, a stabilized form of the explosive nitroglycerine.
In a very real way, the establishment of the prize was its own first controversy. Initially, the creation of the prize caused somewhat of a scandal, and it wasn’t until several years (1901) after his death (1896) that his requests were finally fulfilled with the first series of awards.
His own family opposed the prize; much of his considerable wealth had been bequeathed for its creation rather than to them, so it is easy to understand their objection. In his will, he specifically called for the Swedish Academy of Sciences to award both the Physics and Chemistry awards; the Karolinksa Institute in Stockholm to award the Physiology or Medicine award;
The Nobel Prize is science’s highest award, as is the case with non-science fields too, and it is therefore arguably the most internationally recognized award in the world.
This unique set of volumes focuses on summarizing the Nobel Prize within organic chemistry, as well as the specializations within this specialty. Any reader researching the history of the field of organic chemistry will be interested in this work.
Furthermore, it serves as an outstanding resource for providing a better understanding of the circumstances that led to these amazing discoveries and what has happened as a result, in the years since.
An outstanding resource which enables readers to better understand the conditions that led to these Nobel Prize amazing discoveries
To an extent the roots of organic chemistry have been forgotten or lost and this set of volumes bridges the gap
Unique set of volumes, no other book publication in the field competes and only press releases announcing the prizes from recent years exist
"More than any other branch of chemistry, organic chemists look to history, so the readers will certainly enjoy this compilation "
Appeals to a diverse audience including upcoming as well as modern practicing chemists, and provides the historical context of these discoveries
Table of Contents
Introduction
1902 - Fischer
1910 - Wallach
1912 - Sabatier and Grignard
1950 - Diels and Alder
1965 - Woodward
Author(s)
Biography
Dr. D’Angelo earned his B.S. in Chemistry from the State University of New York at Stony Brook in 2000. While at Stony Brook, he worked in Prof. Peter Tonge’s lab on research towards elucidating the mechanism of action of FAS-II inhibitors for anti-mycobacterium tuberculosis drugs.
While there, he was an active member of the chemistry club, serving as its treasurer for a year. After graduating, he worked as a summer research associate at Stony Brook in Prof. Nancy Goroff’s lab, working towards the synthesis of molecular belts.
He then earned his Ph.D. from the University of Connecticut in 2005 working in the laboratories of Michael B. Smith. There, Dr. D’Angelo worked on the synthesis of 2-nucleobase, 5-hydroxymethyl lactams as putative anti-HIV agents while also investigating the usefulness of the conducting polymer poly-(3,4-ethylinedioxy thiophene) as a chemical reagent. He served as a teaching assistant during most of his 4 years at UCONN and was awarded the Outstanding TA award during one of these years.
After completing his Ph.D., he took a position as a postdoctoral research associate at The Johns Hopkins University in Prof. Gary H. Posner’s lab.
There, Dr. D’Angelo worked on the development of artemisinin derivatives as anti-malarial and anti-toxoplasma gondii derivatives. In 2007, Dr. D’Angelo accepted a position at Alfred University at the rank of Assistant Professor and in 2013, he was awarded tenure and promotion to the rank of Associate Professor at Alfred and awarded promotion to Professor in July 2021.
Dr. D’Angelo’s research has continued to focus on the chemical reactivity of conducting polymers and has been expanded to pedagogical research and scientific ethics. He served as the local ACS section (Corning) chair in 2014 and in 2021, and as the Faculty Senate president during for two consecutive terms, serving in this capacity from 2014-2018 and became Chair of the Chemistry Division at Alfred in 2021.
He is also the author of four books. One, on scientific misconduct is in its 2nd edition and a second book on scientific misconduct intended to be a workbook with hypothetical cases that students can work through.
A third book, written with his Ph.D. advisor outlines a process for using the chemical search engine Reaxsys to teach reactions and the fourth book is an organic chemistry textbook published through the web-based publisher Top Hat. He is also an author of 13 peer-reviewed publications (three in his independent career) and two patents. This four-volume series on organic chemistry and the Nobel Prize is his latest authoring endeavor.
About the book:
First edition published 2023
by CRC Press
Pages : 109
File : PDF, 14MB
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