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Cell and Molecular Biology in pdf


Download This PDF Book: Cell and Molecular Biology What We Know & How We Found Out Annotated CMB 4e An Open Access, Open Education Resource (OER) published under  a Creative Commons (cc-by) license By Gerald Bergtrom, Ph.D, for free.

A grasp of the logic and practice of science is essential to understand the rest of the world around us. To that end, the CMB4e iText remains focused on experimental support for what we know about cell and molecular biology, and on showing students the relationship  of cell structure and function. 

Rather than trying to be a comprehensive reference book, the Basic CMB4e itext selectively details investigative questions, methods and experiments that lead to our understanding of cell biology. This focus is nowhere more obvious than in the chapter learning objectives and in web-links. 

In addition to external online resources, links to the author’s short YouTube voice-over PowerPoint (VOP) videos with optional closed captions are embedded near relevant text. Each video is identified by a play-video symbol and can be opened by clicking a descriptive title or using QR bar codes, such as the example below

The Learning objectives align with content and ask students to use new knowledge to make connections and deepen their understanding of concept and experiment. 

All external links are intended to expand or explain textual content and concepts and to engage student curiosity. All images in the iText and just-in-time VOPs are by the author or are from public domain or Creative Commons (CC) licensed sources. 

Beyond the Basic CMB4e, a freely available Annotated version of the iText contains interactive links and formative assessments in the form of Challenge boxes. 

The Instructors CMB4e version models additional interactive features, including short 25 Words or Less writing assignments that can be incorporated into almost any course  management system, many of which the author has assigned as homework in his flipped, blended course. 

These assessments aim to reinforce writing as well as critical thinking skills. As a Sample Chapter, Chapter 1 of the Instructors version of CMB4e is freely available for download; the complete Instructors version is available on request.

My goal in writing and updating this iText is to make the content engaging, free and comparable in accuracy and currency to commercial textbooks. I encourage instructors to use the interactive features of the iText (critical thought questions, YouTube videos,  etc.) to challenge their students.

About the Author

Dr. Bergtrom is Professor (Emeritus) of Biological Sciences and a former Learning Technology Consultant in the UW-Milwaukee Center for Excellence in Teaching and Learning. Scientific interests include cell and molecular biology and evolution. 

Pedagogic interests are blended and online instruction and the use of technology to serve more active and engaged teaching and learning. He has taught face-to-face, fully online, blended and flipped classes at both undergraduate and graduate levels. 

He also developed and co-instructed Teaching with Technology, an interdisciplinary course aimed at graduate students that they might someday find themselves teaching. 

In his 40+ years of teaching and research experience, he has tested and incorporated pedagogically proven teaching technologies into his courses. His research papers have been  supplemented with publications on active blended, online and flipped classroom methods

Table of Chapters:


Chapter 1: Cell Tour, Life’s Properties and Evolution, Studying Cells

Chapter 2: Basic Chemistry, Organic Chemistry and Biochemistry

Chapter 3: Details of Protein Structure

Chapter 4: Bioenergetics

Chapter 5: Enzyme Catalysis and Kinetics

Chapter 6: Glycolysis, the Krebs Cycle and the Atkins Diet

Chapter 7: Electron Transport, Oxidative Phosphorylation and 


Chapter 8: DNA Structure, Chromosomes and Chromatin

Chapter 9: Details of DNA Replication & DNA Repair

Chapter 10: Transcription and RNA Processing

Chapter 11: The Genetic Code and Translation

Chapter 12: Regulation of Transcription and Epigenetic Inheritance

Chapter 13: Post-Transcriptional Regulation of Gene Expression

Chapter 14: Repetitive DNA, A Eukaryotic Genomic Phenomenon

Chapter 15: DNA Technologies 

Chapter 16: Membrane Structure 

Chapter 17: Membrane Function 

Chapter 18: The Cytoskeleton and Cell Motility 

Chapter 19: Cell Division and the Cell Cycle

Chapter 20: The Origins of Life


Appendix I: List of Illustrations & Sources

Appendix II: Context-Embedded YouTube Videos

Appendix III: Other Useful Links

About The Book:

Publisher ‏ : ‎Creative Commons (cc-by) license

Language ‏ : ‎ English

Pages ‏ : ‎ 629

File : PDF, 9 MB


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