Download This PDF Book: Advanced Organic Chemistry: Part B: Reaction and Synthesis by Carey, Francis A. Published by Springer 5th 2008, for free.
Introduction
The focus of Part B is on the closely interrelated topics of reactions and synthesis. In each of the first twelve chapters, we consider a group of related reactions that have been chosen for discussion primarily on the basis of their usefulness in synthesis.
For each reaction we present an outline of the mechanism, its regio- and stereochemical characteristics, and information on typical reaction conditions.
For the more commonly used reactions, the schemes contain several examples, which may include examples of the reaction in relatively simple molecules and in more complex structures.
The goal of these chapters is to develop a fundamental base of knowledge about organic reactions in the context of synthesis. We want to be able to answer questions such as: What transformation does a reaction achieve?
What is the mechanism of the reaction? What reagents and reaction conditions are typically used? What substances can catalyze the reaction? How sensitive is the reaction to other functional groups and the steric environment? What factors control the stereoselectivity of the reaction? Under what conditions is the reaction enantioselective?
Synthesis is the application of one or more reactions to the preparation of a particular target compound, and can pertain to a single-step transformation or to a number of sequential steps. The selection of a reaction or series of reactions for a synthesis involves making a judgment about the most effective possibility among the available options.
There may be a number of possibilities for the synthesis of a particular compound. For example, in the course of learning about the reactions in Chapter 1 to 12, we will encounter a number of ways of making ketones, as outlined in the scheme that follows
Contents:
Chapter 1. Alkylation of Enolates and Other Carbon Nucleophiles
Chapter 2. Reactions of Carbon Nucleophiles with Carbonyl Compounds
Chapter 3. Functional Group Interconversion by Substitution, Including Protection and Deprotection
Chapter 4. Electrophilic Additions to Carbon-Carbon Multiple Bonds
Chapter 5. Reduction of Carbon-Carbon Multiple Bonds, Carbonyl Groups, and Other Functional Groups
Chapter 6. Concerted Cycloadditions, Unimolecular Rearrangements, and Thermal Eliminations
Chapter 7. Organometallic Compounds of Group I and II Metals
Chapter 8. Reactions Involving Transition Metals
Chapter 9. Carbon-Carbon Bond-Forming Reactions of Compounds of Boron, Silicon, and Tin
Chapter 10. Reactions Involving Carbocations, Carbenes, and Radicals as Reactive Intermediates
Chapter 11. Aromatic Substitution Reactions
Chapter 12. Oxidations
Chapter 13. Multistep Syntheses
About The Book:
Publisher : Springer, 5th edition (2008)
Language : English
Pages : 1347
File : PDF, 18 MB
Free Download the Book: Advanced Organic Chemistry: Part B: Reaction and Synthesis
PS: Share the link with your friends
If the Download link is not working, kindly drop a comment below, so we'll update the download link for you.
Happy downloading!
